AIR EMBOLUS - Human & Disease

AIR EMBOLUS

 AIR EMBOLUS

Most common during operative procedures involving major veins or cardiopulmonary bypass.  ¤ Penetrating trauma to chest (air from lung)  ¤ Insertion or removal of large bore venous lines Carbon dioxide embolus from laparoscopic insufflation.  ¤ Can occur with right to left shunt (VSD, etc.)  ¤ Source of air usually massive.   SIGNS & SYMPTOMS  ¤ Cardiovascular collapse  ¤ Failure to respond to usual resuscitation   TESTS  SPECIFIC TESTS  ¤ EKG may show ischemic changes with coronary air embolus.  ¤ If intraoperative TEE is in use, intracardiac air will be seen differential diagnosis.  ¤ Pulmonary embolism  ° Usually in ward patient with DVT  ° Rarely occurs intraoperatively  ¤ Stroke  ° Intraoperative embolic stroke rarely causes cardiovascular collapse  ¤ Myocardial Infarction  ° Severe ischemia seen on EKG  ¤ Traumatic cardiac tamponade  ° Echocardiogram or surgical exploration  ¤ Tension pneumothorax  ° Hyper-resonant breath sounds  ° Diagnose + treat with needle thoracostomy.   MANAGEMENT  FIRST TO DO  ¤ Position patient head down, left side down  ° Keeps air in apex of right ventricle where slow reabsorption occurs  ¤ Cardiorespiratory support  ° Intubation + mechanical ventilation  ° 100% FiO2 to help reabsorption (creates nitrogen gradient)  ° Volume + pressors as needed
Air Embolus










HISTORY

(What Are The Most Common Causes Of Air Embolism) ?

¤ Most common during operative procedures involving major veins or cardiopulmonary bypass.

¤ Penetrating trauma to chest (air from lung)

¤ Insertion or removal of large bore venous lines Carbon dioxide embolus from laparoscopic insufflation.

¤ Can occur with right to left shunt (VSD).

¤ Source of air usually massive.


SIGNS & SYMPTOMS

(What Hsppens If Air Gets Into "IV") ?

¤ Cardiovascular collapse

¤ Failure to respond to usual resuscitation.

Most common during operative procedures involving major veins or cardiopulmonary bypass.  ¤ Penetrating trauma to chest (air from lung)  ¤ Insertion or removal of large bore venous lines Carbon dioxide embolus from laparoscopic insufflation.  ¤ Can occur with right to left shunt (VSD, etc.)  ¤ Source of air usually massive.   SIGNS & SYMPTOMS  ¤ Cardiovascular collapse  ¤ Failure to respond to usual resuscitation   TESTS  SPECIFIC TESTS  ¤ EKG may show ischemic changes with coronary air embolus.  ¤ If intraoperative TEE is in use, intracardiac air will be seen differential diagnosis.  ¤ Pulmonary embolism  ° Usually in ward patient with DVT  ° Rarely occurs intraoperatively  ¤ Stroke  ° Intraoperative embolic stroke rarely causes cardiovascular collapse  ¤ Myocardial Infarction  ° Severe ischemia seen on EKG  ¤ Traumatic cardiac tamponade  ° Echocardiogram or surgical exploration  ¤ Tension pneumothorax  ° Hyper-resonant breath sounds  ° Diagnose + treat with needle thoracostomy.   MANAGEMENT  FIRST TO DO  ¤ Position patient head down, left side down  ° Keeps air in apex of right ventricle where slow reabsorption occurs  ¤ Cardiorespiratory support  ° Intubation + mechanical ventilation  ° 100% FiO2 to help reabsorption (creates nitrogen gradient)  ° Volume + pressors as needed









TESTS

SPECIFIC TESTS

(How Do You Know If A Patient Has An Air Embolism) ?

¤ EKG may show ischemic changes with coronary air embolus.

¤ If intraoperative TEE is in use, intracardiac air will be seen differential diagnosis.

¤ Pulmonary embolism

° Usually in ward patient with DVT

° Rarely occurs intraoperatively

¤ Stroke

° Intraoperative embolic stroke rarely causes cardiovascular collapse.

¤ Myocardial Infarction

° Severe ischemia seen on EKG

¤ Traumatic cardiac tamponade

° Echocardiogram or surgical exploration

¤ Tension pneumothorax

° Hyper-resonant breath sounds

° Diagnose + treat with needle thoracostomy.

Most common during operative procedures involving major veins or cardiopulmonary bypass.  ¤ Penetrating trauma to chest (air from lung)  ¤ Insertion or removal of large bore venous lines Carbon dioxide embolus from laparoscopic insufflation.  ¤ Can occur with right to left shunt (VSD, etc.)  ¤ Source of air usually massive.   SIGNS & SYMPTOMS  ¤ Cardiovascular collapse  ¤ Failure to respond to usual resuscitation   TESTS  SPECIFIC TESTS  ¤ EKG may show ischemic changes with coronary air embolus.  ¤ If intraoperative TEE is in use, intracardiac air will be seen differential diagnosis.  ¤ Pulmonary embolism  ° Usually in ward patient with DVT  ° Rarely occurs intraoperatively  ¤ Stroke  ° Intraoperative embolic stroke rarely causes cardiovascular collapse  ¤ Myocardial Infarction  ° Severe ischemia seen on EKG  ¤ Traumatic cardiac tamponade  ° Echocardiogram or surgical exploration  ¤ Tension pneumothorax  ° Hyper-resonant breath sounds  ° Diagnose + treat with needle thoracostomy.   MANAGEMENT  FIRST TO DO  ¤ Position patient head down, left side down  ° Keeps air in apex of right ventricle where slow reabsorption occurs  ¤ Cardiorespiratory support  ° Intubation + mechanical ventilation  ° 100% FiO2 to help reabsorption (creates nitrogen gradient)  ° Volume + pressors as needed









MANAGEMENT

FIRST TO DO


¤ Position patient head down, left side down

° Keeps air in apex of right ventricle where slow reabsorption occurs

¤ Cardiorespiratory support

° Intubation + mechanical ventilation

° 100% FiO2 to help reabsorption
(creates nitrogen gradient)

° Volume + pressors as needed

¤ Find and correct source of air embolism

° Close hole in vein

° Flush all lines

° Check bypass machine and connections.

Most common during operative procedures involving major veins or cardiopulmonary bypass.  ¤ Penetrating trauma to chest (air from lung)  ¤ Insertion or removal of large bore venous lines Carbon dioxide embolus from laparoscopic insufflation.  ¤ Can occur with right to left shunt (VSD, etc.)  ¤ Source of air usually massive.   SIGNS & SYMPTOMS  ¤ Cardiovascular collapse  ¤ Failure to respond to usual resuscitation   TESTS  SPECIFIC TESTS  ¤ EKG may show ischemic changes with coronary air embolus.  ¤ If intraoperative TEE is in use, intracardiac air will be seen differential diagnosis.  ¤ Pulmonary embolism  ° Usually in ward patient with DVT  ° Rarely occurs intraoperatively  ¤ Stroke  ° Intraoperative embolic stroke rarely causes cardiovascular collapse  ¤ Myocardial Infarction  ° Severe ischemia seen on EKG  ¤ Traumatic cardiac tamponade  ° Echocardiogram or surgical exploration  ¤ Tension pneumothorax  ° Hyper-resonant breath sounds  ° Diagnose + treat with needle thoracostomy.   MANAGEMENT  FIRST TO DO  ¤ Position patient head down, left side down  ° Keeps air in apex of right ventricle where slow reabsorption occurs  ¤ Cardiorespiratory support  ° Intubation + mechanical ventilation  ° 100% FiO2 to help reabsorption (creates nitrogen gradient)  ° Volume + pressors as needed









GENERAL MEASURES

¤ Avoid air embolism

° Backbleed or aspirate all venous lines during insertion

° Flush or vent any potential air sources prior to unclamping

° Check and tap all bypass lines prior to instituting flow


SPECIFIC THERAPY

¤ If venous lines are in RA or RV, aspirate out the air

¤ If chest is open, aspirate RV apex with needle after positioning

¤ If chest is open, cardiac massage to relieve RV outflow obstruction.

Most common during operative procedures involving major veins or cardiopulmonary bypass.  ¤ Penetrating trauma to chest (air from lung)  ¤ Insertion or removal of large bore venous lines Carbon dioxide embolus from laparoscopic insufflation.  ¤ Can occur with right to left shunt (VSD, etc.)  ¤ Source of air usually massive.   SIGNS & SYMPTOMS  ¤ Cardiovascular collapse  ¤ Failure to respond to usual resuscitation   TESTS  SPECIFIC TESTS  ¤ EKG may show ischemic changes with coronary air embolus.  ¤ If intraoperative TEE is in use, intracardiac air will be seen differential diagnosis.  ¤ Pulmonary embolism  ° Usually in ward patient with DVT  ° Rarely occurs intraoperatively  ¤ Stroke  ° Intraoperative embolic stroke rarely causes cardiovascular collapse  ¤ Myocardial Infarction  ° Severe ischemia seen on EKG  ¤ Traumatic cardiac tamponade  ° Echocardiogram or surgical exploration  ¤ Tension pneumothorax  ° Hyper-resonant breath sounds  ° Diagnose + treat with needle thoracostomy.   MANAGEMENT  FIRST TO DO  ¤ Position patient head down, left side down  ° Keeps air in apex of right ventricle where slow reabsorption occurs  ¤ Cardiorespiratory support  ° Intubation + mechanical ventilation  ° 100% FiO2 to help reabsorption (creates nitrogen gradient)  ° Volume + pressors as needed







.

FOLLOW _ UP

¤ Treat survivors as status-post myocardial infarction complications and prognosis.


COMPLICATIONS

¤ Myocardial Infarction

° Secondary to air embolus entering coronary artery

¤ Anoxic brain injury

° Secondary to prolonged cerebral hypoperfusion.

Most common during operative procedures involving major veins or cardiopulmonary bypass.  ¤ Penetrating trauma to chest (air from lung)  ¤ Insertion or removal of large bore venous lines Carbon dioxide embolus from laparoscopic insufflation.  ¤ Can occur with right to left shunt (VSD, etc.)  ¤ Source of air usually massive.   SIGNS & SYMPTOMS  ¤ Cardiovascular collapse  ¤ Failure to respond to usual resuscitation   TESTS  SPECIFIC TESTS  ¤ EKG may show ischemic changes with coronary air embolus.  ¤ If intraoperative TEE is in use, intracardiac air will be seen differential diagnosis.  ¤ Pulmonary embolism  ° Usually in ward patient with DVT  ° Rarely occurs intraoperatively  ¤ Stroke  ° Intraoperative embolic stroke rarely causes cardiovascular collapse  ¤ Myocardial Infarction  ° Severe ischemia seen on EKG  ¤ Traumatic cardiac tamponade  ° Echocardiogram or surgical exploration  ¤ Tension pneumothorax  ° Hyper-resonant breath sounds  ° Diagnose + treat with needle thoracostomy.   MANAGEMENT  FIRST TO DO  ¤ Position patient head down, left side down  ° Keeps air in apex of right ventricle where slow reabsorption occurs  ¤ Cardiorespiratory support  ° Intubation + mechanical ventilation  ° 100% FiO2 to help reabsorption (creates nitrogen gradient)  ° Volume + pressors as needed













PROGNOSIS

¤ If patient presents with cardiovascular collapse, most do not survive

¤ If air is noticed during embolization (i.e. line placement) and aspirated, prognosis is good

¤ Air embolism in trauma (penetrating lung injury) is usually lethal. 


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